Nano Hydroxyapatite vs Fluoride | Guide With Pros and Cones

You have various options to choose from when it comes to maintaining healthy teeth and gums. Two popular ingredients commonly found in oral care products are nano-hydroxyapatite and fluoride. So, which one is the best choice for your oral health?


    Key Takeaways

      Both nano-hydroxyapatite and fluoride toothpaste have various oral health benefits, including;

  • Nano-hydroxyapatite may be more effective at remineralizing initial caries lesions and reducing sensitivity.
  • Amine fluoride is a well-established cavity fighter and also fights tooth decay.
  • Many products, such as toothpaste and mouthwash, contain both ingredients to provide various oral health benefits as other calcium and phosphate products.
  • Using products as directed by a dental professional about the best choice for oral health is essential.



Choosing the right oral care products is essential when maintaining healthy teeth and gums. Dr. Brite’sExtreme Whitening Toothpaste - Mint is an excellent example of nano-hydroxyapatite toothpaste. 

You can locate fluoride and nano-hydroxyapatite that are frequently present in these products. We will compare nano-hydroxyapatite and fluoride and discuss the best oral health choices.

Green tootjpaste

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What is Nano-hydroxyapatite?

Nano-hydroxyapatite is a synthetic hydroxyapatite, a naturally occurring mineral found in human teeth and bones. Some research suggests the regenerative dentistry aspects of nano-hydroxyapatite toothpaste work more effectively in remineralizing teeth and reducing dental caries. It compares to other oral care ingredients like calcium and phosphate.

Is Nano-hydroxyapatite Toothpaste Better Than Fluoride Toothpaste?

It is difficult to say whether one ingredient is better than the other, as both have oral health benefits. Both are okay to use. Nano-hydroxyapatite may be more effective at dentine remineralization. Fluoride, a well-established cavity fighter, can help to prevent tooth decay. Ultimately, the best choice of toothpaste will depend on your individual needs and concerns.

Can You Use Both Nano-hydroxyapatite and Fluoride?

Yes, using nano-hydroxyapatite and fluoride in your oral care routine is possible. Many products, such as toothpaste andmouthwash, contain both ingredients to provide various oral health benefits as other calcium and phosphate products. However, it is essential to follow the instructions on the product and use it as directed to avoid potential risks from nano-hydroxyapatite.

Mother and daughther washing their teeth

Why Has Fluoride Been the Go-To for So Long?

Fluoride toothpaste has been so successful at preventing cavities that many believe it should get added to all water supplies. But others are questioning whether fluoride toothpaste is good for us.

There are many reasons why fluoride has been the go-to for so long.

  • One of them is that it's cheap. Fluoride is naturally occurring. It occurs in some foods, such as fish and tea, so there's a bit of additional cost to adding it to water supplies.
  • Another reason is that it's easy and convenient. Fluoride is added to water before it goes into the pipes, so you don't have to worry about taking care of your dental hygiene yourself or finding a dentist.
  • Fluoride also helps prevent cavities and strengthens teeth enamel.

Hydroxyapatite vs Fluoride: What's The Difference?

Hydroxyapatite and fluoride are both commonly used ingredients in oral care products, but they work in different ways and have unique benefits.

Hydroxyapatite is a naturally occurring mineral found in human teeth and bones. It is commonly used in oral care products as a teeth whitening agent to improve teeth' appearance. In addition, some research suggests hydroxyapatite toothpaste may be more effective at remineralizing teeth and reducing sensitivity than other oral care ingredients.

On the other hand, fluoride is a chemical element commonly used in oral care products to prevent tooth decay. It reduces cavities caused by acid attacks by strengthening the tooth enamel. Fluoride is also found naturally in many sources of drinking water, which can help to protect against tooth decay.

Both hydroxyapatite and fluoride toothpastes exhibit oral health benefits, but they work differently. Speaking with a dental professional about the best choice for your individual needs and concerns is essential. 

Putting toothpaste on a toothbrush

How Do Hydroxyapatite and Fluoride Differ in Action?

Nano-hydroxyapatite and fluoride exhibit a significant difference in how they work to improve oral health.

The Benefits of Fluoride Toothpaste

  • It helps to protect tooth enamel and prevent cavities.
  • It can strengthen teeth and make them more resistant to decay.
  • It's used in regenerative dentistry to help remineralize damaged tooth surfaces.
  • Reduces the number of bacteria in the mouth by preventing dental caries.
  • It can help to prevent gum disease and bad breath.
  • Easy to use and widely available.


  • Fluoride toothpastes can cause discoloration, dental fluorosis, and staining of your teeth if used in excess or over time. The more you use this type of toothpaste with fluoride toxicity, the more likely you'll experience these stains on your teeth. In the end, this may make them look dull or yellowish.
Blue toothpaste

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The Benefits of Hydroxyapatite Toothpaste

  • Hydroxyapatite toothpaste may be more effective at remineralizing teeth and reducing sensitivity than other oral care ingredients.
  • It can improve the appearance of teeth by whitening and smoothing the surface.
  • It may help to reduce tooth sensitivity by plugging exposed dentin tubules.
  • It can guard against tooth decay by protecting harmful dietary acids.
  • It may be bioactive, osteoconductive, and nontoxic.
  • It can be used with other oral care products or as a standalone toothpaste.


  • The main disadvantage of hydroxyapatite toothpaste is that it can be abrasive and cause excessive wear on the teeth. It may also be too abrasive for sensitive teeth. It can cause damage to the enamel and dentin, leading to sensitivity or tooth erosion.

So, Which One Do You Go For?

As you can see, the debate over fluoride and nano-hydroxyapatite safety has yet to be settled. It's a complex issue with many facets and factors to consider before coming to conclusions. Nevertheless, we hope that this article has been helpful in your research.

Toothpaste as a question mark

 Frequently Asked Questions

1. Is Nano-hydroxyapatite Safe?

Yes, nano-hydroxyapatite is safe. The US Food and Drug Administration (FDA) approved it. The FDA ensures to regulate the manufacturing process of dental products, including toothpaste, mouthwash, and other oral care products. It ensures that these products are safe for human use. The American Dental Association (ADA) also medically recognized nano-hydroxyapatite. 

2. Is Nano-hydroxyapatite Better Than Fluoride?

In some cases, nano-hydroxyapatite could be better than fluoride. nano-hydroxyapatite strengthens your teeth by repairing cavities and preventing them from forming again. Fluoride can only prevent cavities from forming but not fix them once they are created. However, you should always consult your dentist before switching from one type of toothpaste to another. Also, some may cause mild side effects such as gum irritation or sensitivity when used regularly during dental caries prevention or even control dental caries.

3. Can I Wear My Nano-hydroxyapatite Trays If I Have Braces?

Yes, you can wear your nano-hydroxyapatite trays with braces! However, there are some limitations on how long you can wear them daily. Please speak with your dentist or orthodontist for more information about their policies regarding this matter.

4. Can I Use Nano-hydroxyapatite If My Jawbone Receded or My Teeth Were Loose?

Yes, nano-hydroxyapatite is effective in helping to rebuild bone and restore lost bone mass in the jaw area. However, you should only use this product under the guidance of a dentist or doctor who can monitor its effects on your mouth site closely for any adverse reactions or side effects that might occur during treatment.